Neonatal Thyroxine (T4)

PRODUCT NAME: AccuBind Neonatal Thyroxine (T4)
INTENDED USE: The quantitative determination of total thyroxine (T4) concentration in human (neonates) whole blood by a Microplate Enzyme Immunoassay.
PRODUCT OVERVIEW: Determination of hyothyroidism within the first few days of birth has been recognized as the single most important diagnostic test in neonates by the American Thyroid Association. Congenital hypothyroidism is probably the single most commom preventable case of mental retardation. Diagnosis and treatment of congenital hypothyroidism within the first 1-2 months after birth appears to be necessary in order to prevent severe mental retardation. Measurement of thyroxine (T4) and thyroid-stimulating hormone (TSH) in neonates helps in screening for congenital hypothyroidism.

Method: Enzyme Immunoassay, Colorimetric
Principle: Sequential Competitive Assay, Antibody-Coated Plate
Calibrators: 0, 1.5, 3.5, 7.0, 14, 25 µg/dl (lot specific)
(Dried blood spots)
Sample type: Whole blood
Sample volume: 1/8” (3mm) dot of dried whole blood
Measuring range: 0.5 - 25 µg/dl
Reading: Absorbance at 450 nm
Total time: 150 minutes
Storage: 2 - 8 ºC
Kit Contents: N-T4 Calibrators - Dried Blood Spots
Whole Blood Controls
Neo-T4 Elution Reagent
Neo-T4 Conjugate Buffer
NT4 Enzyme Reagent
fT4 Antibody Coated Plate
Wash Concentrate
Substrate Solution
Stop Solution
*Please refer to the product Instruction-For-Use (IFU) for complete details.