| PRODUCT NAME: | β-2-Microglobulin |
| INTENDED USE: | β-2-Microglobulin is an ELISA test system for the quantitative measurement of β-2-Microglobulin in human urine, serum or plasma. |
| PRODUCT OVERVIEW: | β-2-Microglobulin, the light chain of the major histocompatibility complex class I (HLA 1, MHC I) serves as a tumor marker in cases of multiple myeloma, Hodgkin’s disease, chronic lymphatic leukemia, and other non-Hodgkin’s lymphomas. Other diseases (infections, autoimmune diseases) that involve activation of the cellular immune system also cause increased β-2-microglobulin concentrations in serum. β-2-Microglobulin is also used as a marker for evaluating the glomerular filtration rate, for the diagnosis and monitoring of tubulointersticial kidney damage, for monitoring kidney function after a kidney transplant, and monitoring HIV infections. |
TECHNICAL SPECIFICATIONS:
|
| Method: | Enzyme Linked Immune Reaction |
| Capture: | Anti-β-2-microglobulin antibodies (polyclonal, rabbit) |
| Calibrators: | 0, 0.75, 1.5, 3, 6, 12 µg/ml |
| Calibration traceability: | WHO B2M |
| Sample type: | Serum or plasma |
| Sample volume: | 10 µl |
| Measuring range: | 0 - 12 µg/ml |
| Reading: | Absorbance at 450 nm |
| Cut-off: | Serum: 3 µg/ml
Urine: 0 - 0.3 µg/ml |
| Total time: | 65 minutes
|
| Storage: | 2 - 8 ºC
|
| Kit Contents: | Microplate
Calibrators: A, B, C, D, E, F
Controls: Positive & Negative
Enzyme Conjugate
TMB Substrate
Diluent
Stop Solution
Wash Concentrate
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